TITLE
Unravelling the origin and ingredient potential of milk
extracellular vesicles
SHORT PROJECT DESCRIPTION
1$0($1'326,7,21
Ida Emilie Ingvordsen Lindahl, res assistant
START/END DATE
(MAX. 200 WORDS IN TOTAL)
Emilie was employed in a 2 m position as research
assistant in Autumn 2018. She helped out in relation
to coordination and preparing an application to the
independent research council together with MBG. It
was a big research project 2, on the milk genomics
and ingredient potentials aspects involving basis
characterization and potential exploitation of
extracellular vesicles in milk and milk fractions.
Furthermore she helped out in some reportings from
other bigger initiatives, including milk genomics.
Emilie coordinated the inputs and collaboration with
MBG in the DFF application.
9/1/18 11/30/18
,17(51$7,21$/&2//$%25$7,212567$<$%52$'
5(/$7('727+(352-(&7
No
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'2,180%(5
Sending in an application to DFF/big research
project: Unravelling the origin and ingredient potential
of milk extracellular vesicles
Unfortunately we did not get the grant, even though
we got a ok good evaluation. We considered to send
it in the year after, but for various reasons did not do
that.
Specific objectives
To establish a methodological platform for a documentation
of EV in raw milk and in relevant dairy fractions
Validate the experimental approach by accounting for the
occurrence of EV in milk fractions and dairy streams relative
to the appearance of MFGM
Screen a large cohort of milk samples to determine genetic
and non-genetic variability on EV appearance
Ensure that the obtained EV-isolates still hold the desirable
bioactivities by accounting for the presence of nucleic acids
(e.g. miRNA) and conducting bioactivity assays
Test new routes for process technology enabling appropriate
isolation of EV from milk and dairy streams
Project roadmap
1
PICTURE RELATED TO THE PROJECT
352-(&73$57,&,3$17 6 1$0($1'$)),/,$7,21 6
Ida Emilie Ingvordsen Lindahl, AU-FOOD
Lotte Bach Larsen, AU-FOOD
Nina Aagaard Poulsen, AU-FOOD
Jan Trige Rasmussen, AU-MBG
Marie Ostenfeld, Arla Foods Ingredients
/2*2 6 2)352-(&73$57,&,3$17 6
08/7,',6&,3/,1$5<&+$5$&7(52)7+(352-(&7
3/($6('(),1($5($6
Collaboration with Department of Molecular Biology,
Laboratory for Protein Chemistry
1(;767(363/($6(,1',&$7(352-(&7352326$/6
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